The very best screen annotation and live markup tool that is available on the market is Training Tools by Milori.
PC Chalkboard allows you to clearly demonstrate software programs to your audience by creating a clear 'sheet' over the application you are demonstrating for you to draw on.
This is a toolset that lets you annotate the screen while using any application. You have some great tools to highlight specific areas, underline, draw freehand and even a great spotlight to keep everyone focussed on the same item.
Training Tools include also utilities to enlarge a portion of the screen, show the keystrokes you hit on your keyboard visually and play sounds or call up files/web pages at the control of a key. For a live trainer in a computerized classroom or for the international presenter these tools are a must.
Here is the detailed profile:
PC Chalkboard allows you to clearly demonstrate software programs to your audience by creating a clear 'sheet' over the application you are demonstrating for you to draw on.
MagLens helps your audience follow your train of thought by magnifying the area around your mouse cursor while you are moving it around the screen. Easily Pause any image to discuss it with your audience.
Finger Prince is a Training Tool that helps you deliver a more dynamic, smoother presentation by putting all of the reference documents, Help files, web pages and sound effects that you may need during your presentation directly at your finger tips.
Audisee displays an explosive "burst" where you click, and pops up a helpful display when you type, so your audience can understand exactly what you are doing and learn from your actions.
A trial version is available for download.
http://www.milori.com/products/trainingtools/
(These guys have had a great unique product since several years and in the past I tried hard to get a license from them to resell it myself under my own brand. That is how good it is.)
Highly recommended as nothing comes close to it.
Robin Good
What Communication Experts Must Know
http://www.masternewmedia.org/